Pulse Oximeters
Best Pulse Oximeters 2025: Oxiline vs Masimo vs Nonin vs Zacurate
Thirty adult volunteers tested the Oxiline Pulse XS Pro, Masimo MightySat, NoninConnect Elite 3240, and Zacurate 500E-B over four weeks. Each device's readings were benchmarked against arterial blood gas and ECG references during rest, motion, and low-perfusion protocols. We also scored ease-of-use, hardware durability, and value based on retail pricing and warranty coverage. Oxiline delivered the best overall balance of clinical accuracy, user experience, and cost efficiency, while Masimo edged out rivals on raw accuracy. Zacurate proved the most affordable with acceptable precision, and Nonin excelled in ruggedness but lagged on app versatility.