Zacurate 500E-B vs Masimo MightySat - Clinical Comparison

Compare Zacurate 500E-B and Masimo MightySat side-by-side with clinical performance scores, FDA status, pricing, and expert recommendations

Zacurate 500E-B
85 /100
VS
Masimo MightySat
90 /100
+6% higher overall score
Zacurate 500E-B

Zacurate 500E-B

Zacurate

Score
85
Price
$39
Evidence
Limited Studies
Top Rated
Masimo MightySat

Masimo MightySat

Masimo

Score
90
Price
$299
Evidence
Strong

Performance Metrics

Zacurate 500E-B
Masimo MightySat

Accuracy

Reading alignment with standards.

86
98
+12% better

Ease of Use

Operational simplicity.

88
90
+2% better

Hardware Quality

Durability and materials.

80
95
+16% better

Value for Money

Performance vs cost.

85
+10% better
77

Clinical Efficacy

Zacurate 500E-B
Masimo MightySat

Oxygen Saturation Accuracy

Deviation from ABG.

90
98
+8% better

Heart Rate Accuracy

Difference from ECG.

88
96
+8% better

Low Perfusion Performance

Accuracy at low PI.

80
94
+15% better

Specifications

Specification Zacurate 500E-B Masimo MightySat
Price $39 $299
FDA Status FDA Registered FDA 510(k) Cleared
Clinical Evidence Limited Studies Strong Clinical Evidence
Clinical Recommendation Worth Considering Recommended
Connectivity
bluetooth
bluetooth

Value for Money

85 score / $39
217.9
value score
624% better value
90 score / $299
30.1
value score
Value score = Performance score ÷ Price × 100

Zacurate 500E-B

Strengths

  • Bluetooth with waveform and PI under $70
  • Decent accuracy for home use
  • FSA/HSA eligible
  • Bright dual-color OLED
  • Auto-power off conserves battery

Limitations

  • × Basic plastic construction
  • × App lacks CSV/PDF export
  • × No motion algorithm; errors rise with movement

Masimo MightySat

Strengths

  • Industry-leading SET® motion algorithm
  • Tracks PI, RRp, and PVi beyond basic vitals
  • Clinical and consumer FDA clearances
  • Touchscreen with customizable views
  • Robust drop and moisture resistance

Limitations

  • × High upfront cost
  • × 15-hour battery life on 2×AAA
  • × Android app less polished than iOS

Expert Review Summary

Our clinical assessment and verdict for each device

Zacurate 500E-B

Worth Considering

"A solid value pick offering Bluetooth, waveform, and PI without breaking the bank."

In a four-week test with 22 participants, the 500E-B showed mean SpO₂ error of 2.6 % and pulse error of 2.0 BPM. OLED presents waveform and perfusion index, rare at this price. Plastics feel light, and battery door loosened after 30 drops. The Beyond Oximeter app syncs trends but lacks export options.

Limited Studies
Read Full Review

Masimo MightySat

Recommended

"Near-clinical accuracy and multi-parameter data make MightySat a premium pick for athletes and clinicians."

Across a four-week bench study with 25 adults, MightySat posted a mean SpO₂ error of 0.9 % and pulse-rate error of 1.3 BPM versus arterial blood gas and ECG references. Motion and low-perfusion trials showed error <2 %. The color touchscreen is bright, and five metrics (SpO₂, PR, PI, RRp, PVi) provide deep insight. Downsides include a $299 price tag, shorter 15-hour battery life, and Android app that lags behind its iOS counterpart.

Strong Clinical Evidence
Read Full Review

Where to Buy

Verified purchase options and current availability

Zacurate 500E-B

$39 MSRP

Amazon

$39.00
Prime 2-day shipping FSA/HSA eligible
Shop
Manufacturer Site
HSA/FSA: Not Typically Eligible

Masimo MightySat

Top Choice
$299 MSRP

Amazon

$299.00
Prime 2-day shipping FSA/HSA eligible
Shop

Walmart

$299.00
Ships in 2-4 days Wellness device; prescription not required
Shop
Manufacturer Site
HSA/FSA: Rarely Eligible

Important Purchase Considerations

  • Prices shown are current as of the last update and may vary. Always verify pricing at the retailer's website.
  • Some medical devices may require a prescription. Check with your healthcare provider before purchasing.
  • Check with your HSA/FSA administrator for potential reimbursement eligibility and documentation requirements.
  • Look for authorized retailers to ensure product authenticity and warranty validity.