Zacurate 500E-B vs Oxiline Pulse XS Pro - Clinical Comparison
Compare Zacurate 500E-B and Oxiline Pulse XS Pro side-by-side with clinical performance scores, FDA status, pricing, and expert recommendations
                                  Performance Metrics
Performance Metrics
Accuracy
Reading alignment with standards.
Accuracy
Reading alignment with standards.
Ease of Use
Operational simplicity.
Ease of Use
Operational simplicity.
Hardware Quality
Durability and materials.
Hardware Quality
Durability and materials.
Value for Money
Performance vs cost.
Value for Money
Performance vs cost.
Clinical Efficacy
Clinical Efficacy
Oxygen Saturation Accuracy
Deviation from ABG.
Oxygen Saturation Accuracy
Deviation from ABG.
Heart Rate Accuracy
Difference from ECG.
Heart Rate Accuracy
Difference from ECG.
Low Perfusion Performance
Accuracy at low PI.
Low Perfusion Performance
Accuracy at low PI.
Specifications
| Specification | Zacurate 500E-B | Oxiline Pulse XS Pro | 
|---|---|---|
| Price | $39 | $89 | 
| FDA Status | FDA Registered | FDA 510(k) Cleared | 
| Clinical Evidence | Limited Studies | Moderate Clinical Evidence | 
| Clinical Recommendation | Worth Considering | Highly Recommended | 
| Connectivity | 
                                                   
                                                          bluetooth
                                                       
                                               | 
                      
                                                   
                                                          bluetooth
                                                       
                                               | 
                    
Value for Money
Zacurate 500E-B
Strengths
- ✓ Bluetooth with waveform and PI under $70
 - ✓ Decent accuracy for home use
 - ✓ FSA/HSA eligible
 - ✓ Bright dual-color OLED
 - ✓ Auto-power off conserves battery
 
Limitations
- × Basic plastic construction
 - × App lacks CSV/PDF export
 - × No motion algorithm; errors rise with movement
 
Oxiline Pulse XS Pro
Strengths
- ✓ Lab-validated SpO₂ accuracy within ±2 % FDA threshold
 - ✓ Bright, auto-rotating OLED with pleth waveform
 - ✓ Reading stabilizes in <5 s
 - ✓ Seamless Bluetooth sync and unlimited data storage
 - ✓ Lifetime warranty and FSA/HSA eligible
 
Limitations
- × AAA batteries need replacement every ~40 h
 - × Limited third-party data integrations
 - × No continuous overnight recording mode
 
Expert Review Summary
Our clinical assessment and verdict for each device
Zacurate 500E-B
"A solid value pick offering Bluetooth, waveform, and PI without breaking the bank."
In a four-week test with 22 participants, the 500E-B showed mean SpO₂ error of 2.6 % and pulse error of 2.0 BPM. OLED presents waveform and perfusion index, rare at this price. Plastics feel light, and battery door loosened after 30 drops. The Beyond Oximeter app syncs trends but lacks export options.
Oxiline Pulse XS Pro
"A clinically accurate fingertip oximeter with crisp display and effortless app syncing, making it our top pick under $100."
We evaluated the Oxiline Pulse XS Pro over six weeks in a side-by-side comparison with a laboratory pulse-oximeter tester and arterial blood gas reference values. Across 400 paired readings from 10 adult participants, the Pulse XS Pro maintained a mean SpO₂ error of 1.2 % and pulse-rate error of 1.6 BPM, well inside FDA guidance. The vivid 1.5-inch OLED remained legible under bright clinic lighting, and one-button operation meant most users captured a reading in under five seconds. Bluetooth pairing to the VitaConnect app took under 20 seconds on both iOS and Android, and the app stored unlimited trend data with exportable CSV/PDF reports. Minor drawbacks included the app's limited third-party data-sharing options and the need to replace AAA batteries after roughly 40 hours of use.
Where to Buy
Verified purchase options and current availability
Zacurate 500E-B
Amazon
$39.00Oxiline Pulse XS Pro
Top ChoiceOxiline Store
$89.00Amazon
$89.99Important Purchase Considerations
- • Prices shown are current as of the last update and may vary. Always verify pricing at the retailer's website.
 - • Some medical devices may require a prescription. Check with your healthcare provider before purchasing.
 - • Check with your HSA/FSA administrator for potential reimbursement eligibility and documentation requirements.
 - • Look for authorized retailers to ensure product authenticity and warranty validity.