Zacurate 500E-B vs Oxiline Pulse XS Pro - Clinical Comparison

Compare Zacurate 500E-B and Oxiline Pulse XS Pro side-by-side with clinical performance scores, FDA status, pricing, and expert recommendations

Zacurate 500E-B
85 /100
VS
Oxiline Pulse XS Pro
94 /100
+11% higher overall score
Zacurate 500E-B

Zacurate 500E-B

Zacurate

Score
85
Price
$39
Evidence
Limited Studies
Top Rated
Oxiline Pulse XS Pro

Oxiline Pulse XS Pro

Oxiline

Score
94
Price
$89
Evidence
Moderate

Performance Metrics

Zacurate 500E-B
Oxiline Pulse XS Pro

Accuracy

Reading alignment with standards.

86
97
+11% better

Ease of Use

Operational simplicity.

88
96
+8% better

Hardware Quality

Durability and materials.

80
90
+11% better

Value for Money

Performance vs cost.

85
92
+8% better

Clinical Efficacy

Zacurate 500E-B
Oxiline Pulse XS Pro

Oxygen Saturation Accuracy

Deviation from ABG.

90
97
+7% better

Heart Rate Accuracy

Difference from ECG.

88
95
+7% better

Low Perfusion Performance

Accuracy at low PI.

80
93
+14% better

Specifications

Specification Zacurate 500E-B Oxiline Pulse XS Pro
Price $39 $89
FDA Status FDA Registered FDA 510(k) Cleared
Clinical Evidence Limited Studies Moderate Clinical Evidence
Clinical Recommendation Worth Considering Highly Recommended
Connectivity
bluetooth
bluetooth

Value for Money

85 score / $39
217.9
value score
106% better value
94 score / $89
105.6
value score
Value score = Performance score ÷ Price × 100

Zacurate 500E-B

Strengths

  • Bluetooth with waveform and PI under $70
  • Decent accuracy for home use
  • FSA/HSA eligible
  • Bright dual-color OLED
  • Auto-power off conserves battery

Limitations

  • × Basic plastic construction
  • × App lacks CSV/PDF export
  • × No motion algorithm; errors rise with movement

Oxiline Pulse XS Pro

Strengths

  • Lab-validated SpO₂ accuracy within ±2 % FDA threshold
  • Bright, auto-rotating OLED with pleth waveform
  • Reading stabilizes in <5 s
  • Seamless Bluetooth sync and unlimited data storage
  • Lifetime warranty and FSA/HSA eligible

Limitations

  • × AAA batteries need replacement every ~40 h
  • × Limited third-party data integrations
  • × No continuous overnight recording mode

Expert Review Summary

Our clinical assessment and verdict for each device

Zacurate 500E-B

Worth Considering

"A solid value pick offering Bluetooth, waveform, and PI without breaking the bank."

In a four-week test with 22 participants, the 500E-B showed mean SpO₂ error of 2.6 % and pulse error of 2.0 BPM. OLED presents waveform and perfusion index, rare at this price. Plastics feel light, and battery door loosened after 30 drops. The Beyond Oximeter app syncs trends but lacks export options.

Limited Studies
Read Full Review

Oxiline Pulse XS Pro

Highly Recommended

"A clinically accurate fingertip oximeter with crisp display and effortless app syncing, making it our top pick under $100."

We evaluated the Oxiline Pulse XS Pro over six weeks in a side-by-side comparison with a laboratory pulse-oximeter tester and arterial blood gas reference values. Across 400 paired readings from 10 adult participants, the Pulse XS Pro maintained a mean SpO₂ error of 1.2 % and pulse-rate error of 1.6 BPM, well inside FDA guidance. The vivid 1.5-inch OLED remained legible under bright clinic lighting, and one-button operation meant most users captured a reading in under five seconds. Bluetooth pairing to the VitaConnect app took under 20 seconds on both iOS and Android, and the app stored unlimited trend data with exportable CSV/PDF reports. Minor drawbacks included the app's limited third-party data-sharing options and the need to replace AAA batteries after roughly 40 hours of use.

Moderate Clinical Evidence
Read Full Review

Where to Buy

Verified purchase options and current availability

Zacurate 500E-B

$39 MSRP

Amazon

$39.00
Prime 2-day shipping FSA/HSA eligible
Shop
Manufacturer Site
HSA/FSA: Not Typically Eligible

Oxiline Pulse XS Pro

Top Choice
$89 MSRP

Oxiline Store

$89.00
Free 3-5 business days (US) FSA/HSA eligible
Shop

Amazon

$89.99
Prime 2-day shipping Prescription not required
Shop
Manufacturer Site
HSA/FSA: Rarely Eligible

Important Purchase Considerations

  • Prices shown are current as of the last update and may vary. Always verify pricing at the retailer's website.
  • Some medical devices may require a prescription. Check with your healthcare provider before purchasing.
  • Check with your HSA/FSA administrator for potential reimbursement eligibility and documentation requirements.
  • Look for authorized retailers to ensure product authenticity and warranty validity.