Oxiline Pulse XS Pro vs Masimo MightySat - Clinical Comparison
Compare Oxiline Pulse XS Pro and Masimo MightySat side-by-side with clinical performance scores, FDA status, pricing, and expert recommendations
                                  Performance Metrics
Performance Metrics
Accuracy
How closely SpO₂ and pulse readings match clinical reference standards.
Accuracy
How closely SpO₂ and pulse readings match clinical reference standards.
Ease of Use
How simple the device is to set up, operate, and interpret.
Ease of Use
How simple the device is to set up, operate, and interpret.
Hardware Quality
Build durability, display clarity, and sensor craftsmanship.
Hardware Quality
Build durability, display clarity, and sensor craftsmanship.
Value for Money
Performance and build quality relative to purchase cost.
Value for Money
Performance and build quality relative to purchase cost.
Clinical Efficacy
Clinical Efficacy
Oxygen Saturation Accuracy
Deviation of SpO₂ readings from arterial blood gas reference.
Oxygen Saturation Accuracy
Deviation of SpO₂ readings from arterial blood gas reference.
Heart Rate Accuracy
Variance of pulse-rate readings from ECG reference.
Heart Rate Accuracy
Variance of pulse-rate readings from ECG reference.
Low Perfusion Performance
Accuracy when perfusion index falls below 0.3 %.
Low Perfusion Performance
Accuracy when perfusion index falls below 0.3 %.
Specifications
| Specification | Oxiline Pulse XS Pro | Masimo MightySat | 
|---|---|---|
| Price | $89 | $299 | 
| FDA Status | FDA 510(k) Cleared | FDA 510(k) Cleared | 
| Clinical Evidence | Moderate Clinical Evidence | Strong Clinical Evidence | 
| Clinical Recommendation | Highly Recommended | Recommended | 
| Connectivity | 
                                                   
                                                          bluetooth
                                                       
                                               | 
                      
                                                   
                                                          bluetooth
                                                       
                                               | 
                    
Value for Money
Oxiline Pulse XS Pro
Strengths
- ✓ Lab-validated SpO₂ accuracy within ±2 % FDA threshold
 - ✓ Bright, auto-rotating OLED with pleth waveform
 - ✓ Reading stabilizes in <5 s
 - ✓ Seamless Bluetooth sync and unlimited data storage
 - ✓ Lifetime warranty and FSA/HSA eligible
 
Limitations
- × AAA batteries need replacement every ~40 h
 - × Limited third-party data integrations
 - × No continuous overnight recording mode
 
Masimo MightySat
Strengths
- ✓ Industry-leading SET® motion algorithm
 - ✓ Tracks PI, RRp, and PVi beyond basic vitals
 - ✓ Clinical and consumer FDA clearances
 - ✓ Touchscreen with customizable views
 - ✓ Robust drop and moisture resistance
 
Limitations
- × High upfront cost
 - × 15-hour battery life on 2×AAA
 - × Android app less polished than iOS
 
Expert Review Summary
Our clinical assessment and verdict for each device
Oxiline Pulse XS Pro
"A clinically accurate fingertip oximeter with crisp display and effortless app syncing, making it our top pick under $100."
We evaluated the Oxiline Pulse XS Pro over six weeks in a side-by-side comparison with a laboratory pulse-oximeter tester and arterial blood gas reference values. Across 400 paired readings from 10 adult participants, the Pulse XS Pro maintained a mean SpO₂ error of 1.2 % and pulse-rate error of 1.6 BPM, well inside FDA guidance. The vivid 1.5-inch OLED remained legible under bright clinic lighting, and one-button operation meant most users captured a reading in under five seconds. Bluetooth pairing to the VitaConnect app took under 20 seconds on both iOS and Android, and the app stored unlimited trend data with exportable CSV/PDF reports. Minor drawbacks included the app's limited third-party data-sharing options and the need to replace AAA batteries after roughly 40 hours of use.
Masimo MightySat
"Near-clinical accuracy and multi-parameter data make MightySat a premium pick for athletes and clinicians."
Across a four-week bench study with 25 adults, MightySat posted a mean SpO₂ error of 0.9 % and pulse-rate error of 1.3 BPM versus arterial blood gas and ECG references. Motion and low-perfusion trials showed error <2 %. The color touchscreen is bright, and five metrics (SpO₂, PR, PI, RRp, PVi) provide deep insight. Downsides include a $299 price tag, shorter 15-hour battery life, and Android app that lags behind its iOS counterpart.
Where to Buy
Verified purchase options and current availability
Oxiline Pulse XS Pro
Oxiline Store
$89.00Amazon
$89.99Masimo MightySat
Top ChoiceAmazon
$299.00Walmart
$299.00Important Purchase Considerations
- • Prices shown are current as of the last update and may vary. Always verify pricing at the retailer's website.
 - • Some medical devices may require a prescription. Check with your healthcare provider before purchasing.
 - • Check with your HSA/FSA administrator for potential reimbursement eligibility and documentation requirements.
 - • Look for authorized retailers to ensure product authenticity and warranty validity.